Search results for "Appropriate use"

showing 10 items of 13 documents

Opportunities and challenges for drug development: public-private partnerships, adaptive designs and big data

2016

Drug development faces the double challenge of increasing costs and increasing pressure on pricing. To avoid that lack of perceived commercial perspective will leave existing medical needs unmet, pharmaceutical companies and many other stakeholders are discussing ways to improve the efficiency of drug Research and Development. Based on an international symposium organized by the Medical School of the University of Duisburg-Essen (Germany) and held in January 2016, we discuss the opportunities and challenges of three specific areas, i.e., public-private partnerships, adaptive designs and big data. Public-private partnerships come in many different forms with regard to scope, duration and typ…

0301 basic medicineLeverage (finance)Big dataMedizinReviewAppropriate useadaptive trial design03 medical and health sciencesDrug DevelopmentInformed consentinvestigator-initiated studiesbig dataPharmacology (medical)RepurposingPharmacologyInformed Consentbusiness.industryManagement sciencelcsh:RM1-950Public relationsEuphemismpublic-private partnershipPublic–private partnership030104 developmental biologylcsh:Therapeutics. PharmacologyDrug developmentPrivacyBusinesspublic–private partnershipFrontiers in Pharmacology
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Revealing deterministic structures in click-evoked otoacoustic emissions.

2000

Click-evoked otoacoustic emissions (CEOAEs) were studied by means of recurrence quantification analysis (RQA) and were found to be endowed with a relevant amount of deterministic structuring. Such a structure showed highly significant correlation with the clinical evaluation of the signal over a data set including 56 signals. Moreover, 1) one of the RQA variables, Trend, was very sensitive to phase transitions in the dynamical regime of CEOAEs, and 2) appropriate use of principal component analysis proved able to isolate the individual character of the studied signals. These results are of general interest for the study of auditory signal transduction and generation mechanisms.

Adultmedicine.medical_specialtyPhysiologyOtoacoustic Emissions SpontaneousOtoacoustic emissionReproducibility of ResultsTransduction (psychology)BiologyAudiologyAppropriate useSignalCorrelationmedicine.anatomical_structureAcoustic StimulationRecurrence quantification analysisPhysiology (medical)Principal component analysismedicineReaction TimeAuditory systemHumansBiological systemJournal of applied physiology (Bethesda, Md. : 1985)
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Using Technologies to Teach Different Age Groups Meaningfully

2018

Increasing use of technologies in schools is inevitable as technologies provide new opportunities for innovative ways of learning and naturally attract students’ attention as modern and even playful tools. However, use of technologies can be most effective if the tasks are suitable for the specific age of students. It is necessary for teachers to be aware of cognitive development of children in different age groups in order to offer teaching methods and tasks that can be well-perceived by students and that foster the development of their cognitive abilities. This chapter provides a brief overview of cognitive development of children at different school ages, including development of executi…

ComprehensionAge groupsbusiness.industryTeaching methodCognitive developmentMathematics educationInformation technologyCognitionExecutive functionsAppropriate usebusinessPsychology
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Transcultural adaptation and validation of Italian Selfcarediabetic foot questionnaire

2021

[Abstract] The Italian Self care diabetic foot questionnaire, (SDFQ-IT) is considered a dia-betic foot self-care evaluation tool with 16 questions for assessing diabetic foothealth disorders. To date, SDFQ has been validated in different languages, butan Italian version was lacking. Consequently, the purpose of this study was totranslate and validate the Italian version of the SDFQ-I T (SDFQ-IT). A suitablemethod was developed for the translation protocol and cross-cultural valida-tion from Spanish to Italian. Regarding the total marks from each sub-scale,agreement degrees, and confidence were analysed using the Cronbach's α andintraclass correlation coefficient (IC C), respectively. In add…

Encuestamedicine.medical_specialtyIntraclass correlationAutocuidadoDermatologyPie diabéticoAppropriate useEnquestesAutogestión030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineCronbach's alphaSurveys and QuestionnairesDiabetes MellitusmedicineSelf-managementHumans030212 general & internal medicineself‐careReliability (statistics)LanguageDiabetisbusiness.industryQuestionnairequestionnaireReproducibility of ResultsOriginal ArticlesRepeatabilitymedicine.diseaseDiabetic footDiabetic FootSelf CareExtremitatsDiabetic footItalyself‐managementSelf carePhysical therapyOriginal ArticleSurgerySelf-carebusinessFoot (unit)
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The use of videogames as digital leisure among people with autism spectrum disorder

2021

espanolEl ocio digital, y en concreto los videojuegos, estan cada vez mas afianzados en todos los segmentos de la sociedad. Hacer un uso adecuado de ellos implica un desafio para los usuarios, familias y profesionales. En el presente estudio se aborda de manera especifica el uso que las personas con Trastornos del Espectro Autista hacen de este tipo de entretenimiento y se presentan una serie de recomendaciones que toman en cuenta las caracteristicas de esta poblacion. Para ello, se elaboro un cuestionario ad hoc y se administro a 67 personas con TEA de diferentes edades. Los resultados reflejan que los videojuegos son un tipo de juego muy popular entre las personas con TEA, se perciben com…

H1-99video-game technologyHD7255-7256education.field_of_studySocial PsychologyPopulationPersonaasdVocational rehabilitation. Employment of people with disabilitiesAppropriate useBF1-990EducationSocial sciences (General)Psychiatry and Mental healthdigital leisurePsychologyPshychiatric Mental HealtheducationPsychologyHumanitiesSiglo Cero Revista Española sobre Discapacidad Intelectual
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Uses and Misuses of Data

2018

Higher education is awash with data with more coming every year. Much of this is due to accountability reasons and growing interest from stakeholders (internal and external). New technologies have increasingly allowed more powerful analytics and deeper dives into data. However the increasing pressures and new technologies have brought significant questions on how data is used and its relevance. This chapter examines how data is used within higher education and an extended discussion of how it has been misused. The chapter concludes with three suggestions on how institutions can do to reduce the likelihood of the misuse of data and the role of institutional research could play in facilitatin…

Higher educationEmerging technologiesinstituutiotväärinkäyttöAppropriate usekäyttöPolitical scienceanalysointiinstitutional researchRelevance (information retrieval)yliopistotbusiness.industry05 social sciences050301 educationPublic relationsInstitutional researchuniversity planningdataAnalyticskorkea-asteen kolutushigher educationAccountabilitytutkimus0509 other social sciences050904 information & library sciencesbusiness0503 education
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Multilevel Modeling: Research-Based Lessons for Substantive Researchers

2017

Organizations are multilevel systems. Most organizational phenomena are multilevel in nature, and their understanding involves variables (e.g., antecedents and consequences) that reside at different levels. The investigation of these phenomena requires appropriate analytical methods: multilevel modeling. These techniques are becoming increasingly popular among organizational psychology and organizational behavior (OPOB) researchers. In this article we review the literature that has evaluated the performance of multilevel modeling techniques to test multilevel direct and indirect effects and cross-level interactions. We also provide guidelines for OPOB researchers about the appropriate use …

Multilevel systemsOrganizational Behavior and Human Resource ManagementSocial PsychologyManagement science05 social sciencesMultilevel model050401 social sciences methodsAppropriate useStructural equation modeling0504 sociologyOrganizational behavior0502 economics and businessResearch basedResearch developmentIndustrial and organizational psychologyPsychology050203 business & managementApplied PsychologyAnnual Review of Organizational Psychology and Organizational Behavior
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Seasonal pattern and amplitude: a logical framework to analyse seasonality in tourism. An application to bed occupancy in Sicilian hotels

2011

Many studies have investigated seasonality in tourism in terms of its causes and impacts, from both theoretical and applied perspectives. However, the definition of seasonality and, most of all, its application and measurement have not received the same degree of attention. In recognizing that seasonality has two main facets – pattern and amplitude – this paper critically examines the main seasonality measures proposed in the tourism literature, classifying them according to their properties and their most appropriate use. The framework then proposed is used to analyse a standard and comparable efficiency measure, such as the bed occupancy rate of Sicilian accommodation establishments, pla…

Seasonality measurebusiness.industryhotels occupancyGeography Planning and DevelopmentSeasonalitymedicine.diseaseAppropriate useBed Occupancylanguage.human_languageLogical frameworkAmplitudeGeographyTourism Leisure and Hospitality ManagementmedicineEconometricslanguageOperations managementSettore SECS-S/05 - Statistica Socialebusinesstourism demandAccommodationSicilianSicilyTourism
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Use of Combination Statin and Bile Acid Sequestrant Therapy to Treat Dyslipidemia

2015

Lipid management guidelines promulgated around the world continue to emphasize the need to reduce serum levels of low-density lipoprotein cholesterol (LDL-C) in order to reduce risk for acute cardiovascular events in both the primary and secondary prevention settings [1–3]. There is growing consensus that when it comes to LDL-C management, lower is better with no apparent lower limit that is discernible from current evidence, i.e., there is greater and greater benefit as LDL-C decreases with no apparent loss in safety [4–8]. Dyslipidemia and coronary artery disease (CAD) are widely prevalent throughout the world. Considerable effort continues to be focused on expanding the appropriate use o…

Secondary preventionmedicine.medical_specialtyStatinBile acidbusiness.industrymedicine.drug_classmedicine.diseaseAppropriate useCoronary artery diseaseBile acid sequestrantMedicinelipids (amino acids peptides and proteins)businessIntensive care medicineDyslipidemiaLipoprotein cholesterol
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Enseñanza de las ciencias : revista de investigación y experiencias didácticas

2006

Resumen basado en el de la publicación Resumen en inglés Se muestra el importante papel de uno de los instrumentos más comunes, el péndulo, en la construcción del paradigma newtoniano. Del análisis de algunas aplicaciones interesantes llevadas a cabo por los mejores científicos de ese tiempo, se concluye que el uso apropiado del péndulo en el aula puede ser una manera fácil de introducir la evolución histórica y epistemológica de conceptos físicos básicos. ESP

media_common.quotation_subjectGalileuAppropriate useAnàlisi del moviment planetariEducationmétodo de enseñanzaPhysics::Popular PhysicsConservació de l'energiaNewton i el pèndulHuygens i el pèndulLlei de l'isocronisme pendularSistemes de referència inercials o privilegiatsMedició del tempsmedia_commonconstrucción de modelosfísicaepistemologíaPhysics::Physics EducationArtHooke i el pèndulForça centrífugaEpistemologyeducación científicaPhysical Conceptshistoria de la educaciónPèndul de Focaulthistoria de la ciencia y de las humanidadesMassa pes i teoria de la gravitació universalCartography
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